Visibly reduce wrinkles
and restore your glow —
without injectables.
24K gold microneedles deliver PDRN, Exosomes and B12 directly beyond your skin's barrier — where traditional creams simply can't reach. A complete facial treatment. At home. In 20 minutes.
Why HoMEso Works
When Creams Don't
Traditional serums sit on the surface of your skin. HoMEso uses 24K gold microneedles to deliver three targeted actives exactly where they need to go — below the skin's barrier.
PDRN is a regenerative active used in aesthetic clinics worldwide to visibly stimulate collagen and firm the skin. Delivered directly below the surface, it reduces the appearance of fine lines and restores density over a course of treatments — with no needles, no clinic, no downtime.
Exosomes carry growth factors that activate your skin's own renewal process. Applied via micro-infusion, they visibly improve tone, texture and radiance — making them one of the most talked-about advances in modern skincare. Now available in an at-home treatment for the first time.
Vitamin B12 restores natural skin luminosity. Our nano-fragmented hyaluronic acid hydrates at a depth no topical cream can reach. Four targeted peptides visibly smooth expression lines — leaving skin looking brighter, plumper and more even after every treatment.
Serums that stay on the surface
can't change your skin.
HoMEso goes deeper.
The skin's outer barrier blocks most active ingredients from ever reaching where they work. HoMEso's 24K gold hollow microneedles open a temporary pathway — delivering PDRN, Exosomes and B12 precisely where they can stimulate real, visible change.
Open the Pathway
24K gold hollow microneedles gently create a temporary opening in the skin's surface — painlessly and precisely, at just 0.5mm depth. The channel closes within minutes.
Deliver the Actives
As you stamp, the PDRN and Exosome serum flows through the needles and is delivered directly below the skin's barrier — not pooled on the surface like a standard serum.
Visibly Improve Over Time
PDRN stimulates collagen. Exosomes trigger skin renewal. Peptides smooth expression lines. Results appear within 24–48 hours and continue to improve with each treatment.
Real Results.
Real Customers.
See verified results for the skin concerns HoMEso targets most.
Visibly reduce the appearance of fine lines and wrinkles — without injectables.
PDRN stimulates collagen production below the surface of the skin — rebuilding what naturally declines with age. Our peptide complex targets expression lines directly. Results are visible from the first treatment and continue to improve with each session.
- Visibly smoother skin after 1–3 treatments
- Firmer, plumper skin as collagen rebuilds over 6–8 weeks
- Targets fine lines where creams can't reach
- Peptide complex visibly smooths expression lines
- Results compound — the longer you use it, the better it gets
Recommended by Dermatologists
Skin specialists on why they recommend HoMEso — and what makes PDRN and Exosomes different.
"I use PDRN micro-infusion in my clinic every week. HoMEso brings the same active ingredient and delivery approach into a well-designed home device. I recommend it to patients who want to maintain results between appointments — or avoid clinic visits altogether."
"When patients ask what they can do at home to get real results, I tell them HoMEso. The PDRN and Exosome formula is the real deal — and the hollow micro-needle delivery system is the right way to get those ingredients where they actually work."
"Exosomes and PDRN are not marketing terms — they are among the most clinically substantiated actives in modern dermatology. HoMEso is the first at-home device I've seen that combines both with a delivery method capable of getting them past the skin barrier."
What Our Customers Are Saying
4.8 stars from 1,289 verified reviews.
"I've tried a lot of at-home devices. HoMEso is the first that actually delivered visible results — firmer, more luminous skin from the very first use. Six weeks in and the improvement in my fine lines and texture has been significant."
"I was spending €250 every six weeks at a skin clinic. After trying HoMEso I got comparable results — firmer skin, reduced lines, improved texture — at home in 20 minutes. Three months in and results keep improving."
"My dermatologist noticed the improvement at my last check-up and asked what I'd added to my routine. When I showed her HoMEso she wanted to know more. I wouldn't have expected these results from an at-home device."
Showing 3 of 1,289 verified reviews
Get a Professional Glow at Home — Without the Clinic Price
See how HoMEso compares to clinic micro-infusion and other at-home devices.
| HoMEso Premium Kit BEST VALUE | Clinic Micro-Infusion | Derma Roller / Other | |
|---|---|---|---|
| PDRN & Exosomes | ✔ Included | Varies by clinic | ✗ Not available |
| Results visible | ✔ After 1 treatment | 1–3 days | Several sessions |
| Cost per treatment | ✔ ~€8 per session | €200–400 | <€10 (no serum) |
| Appointment needed | ✔ No | ✗ Yes | ✔ No |
| Downtime | ✔ 1–2 days mild redness | 2–5 days | Variable |
| Personalized serum | ✔ Yes — targeted formula | ✔ Yes | ✗ No |
| Dermatologist approved | ✔ Yes | ✔ Yes | Varies |
| Made in Italy | ✔ Yes | — | ✗ No |
| Guarantee | ✔ 30-day money-back | No refund | Varies |
See How Quick & Easy It Is
A complete 20-minute home facial. No appointments. No downtime.
Watch the 2-minute Tutorial
See the full treatment from start to finish
1. Cleanse
Start with a clean, dry face. Remove all makeup and skincare products to prepare your skin for treatment.
2. Fill & Prepare
Pour one ampoule of PDRN & Exosome Serum into the applicator. Attach the sterile needle head. Leave upside-down for 1–2 minutes to prime.
3. Treat
Stamp evenly across the face with 2–3 light passes. The serum infuses directly as you stamp. Pat in remaining serum and leave overnight to work.
4. Aftercare
Apply the included Aftertreatment Tester to calm and protect. Avoid fragrance, acids, and retinol for 2–3 days. Repeat every 2 weeks.
Choose Your Treatment.
Up to 60% OFF — This Weekend Only.
HoMEso Premium Rejuvenation Kit with PDRN, Exosomes & B12 — our most advanced formula at our lowest ever price.
Premium Rejuvenation Kit
Everything you need for one full month of treatment — 2 complete facial sessions at home.
That's just ~€44.95 per treatment
- PDRN & Exosome Serum Booster
- 24K hollow micro-needle applicator
- Sterile single-use needle heads
- Aftertreatment Tester included
- First visible results after one use
- Made in Italy · Dermatologist approved
Or 3 × €29.97 interest-free with Klarna
3× Premium Rejuvenation Kit
Three complete monthly kits — the full recommended course for visible, lasting results.
That's just ~€59.97 per monthly kit — vs €300+ at a clinic
- 3× 24K hollow micro-needle applicators
- 3× PDRN & Exosome Peptide Serum
- 3× B12 Ampoule
- 3× Aftertreatment Tester
- Results build progressively over 3 months
- Made in Italy · Dermatologist approved
Or 4 × €44.98 interest-free with Klarna · Sezzle · Afterpay
5 Reasons to Choose HoMEso
A single clinic micro-infusion session costs €200–400. HoMEso delivers the same active ingredients at home for as little as €8 per treatment.
The only at-home kit that contains both PDRN and Exosomes — the regenerative actives used by dermatologists in aesthetic clinics worldwide.
A complete micro-infusion treatment in 20 minutes at home. No booking, no travel, no waiting room.
24K gold hollow needles at 0.5mm — above the nerve layer. No pain, no numbing cream required. Most customers describe it as gentle pressure and nothing more.
Formulated and manufactured in Italy to EU cosmetic safety standards. Fragrance-free. Dermatologist approved. Sterile-packed needle tips.
Try It for 30 Days — Risk Free
Order the HoMEso Premium Kit and use it for a full 30 days. If you don't see a visible difference in your skin, contact us for a complete refund. No questions, no conditions. We stand behind every kit we sell.
Your order is fully protected. If it doesn't work for you, you pay nothing.
Rivoluzionario! La tua pelle te ne sarà grata...
Finalmente un prodotto di cura della pelle che offre risultati!
Il Kit di Ringiovanimento HoMEso è una vera innovazione di bellezza. È pura magia!...
Funziona! Non solo le creme sono belle, ma offrono risultati...
Il marchio sta cambiando il nostro approccio alla cura della pelle. Lo adoriamo!
Rivoluzionario! La tua pelle te ne sarà grata...
Finalmente un prodotto di cura della pelle che offre risultati!
Il Kit di Ringiovanimento HoMEso è una vera innovazione di bellezza. È pura magia!...
Funziona! Non solo le creme sono belle, ma offrono risultati...
Il marchio sta cambiando il nostro approccio alla cura della pelle. Lo adoriamo!
Rivoluzionario! La tua pelle te ne sarà grata...
Finalmente un prodotto di cura della pelle che offre risultati!
Il Kit di Ringiovanimento HoMEso è una vera innovazione di bellezza. È pura magia!...
Funziona! Non solo le creme sono belle, ma offrono risultati...
Il marchio sta cambiando il nostro approccio alla cura della pelle. Lo adoriamo!
Common Questions
PDRN is a regenerative active derived from salmon DNA, clinically used to stimulate collagen production and accelerate skin repair. Exosomes are tiny messengers that carry growth factors between skin cells, activating the skin's own renewal process. Both are used in professional aesthetic treatments worldwide — and HoMEso is the only at-home kit that delivers both, directly below the skin's surface.
Most customers notice a visible glow and skin-tightening effect after their first treatment. More significant results — reduced fine lines, improved texture, brighter tone — typically appear after 2–4 treatments (4–8 weeks). Use the kit once every two weeks for best results. With consistent use over 3+ months, results continue to build.
No. The 24K gold hollow needles are 0.5mm — they stay within the upper skin layer, above the nerve endings. Most customers describe the sensation as light pressure. No numbing cream or anaesthesia needed.
A derma roller drags angled needles across the skin and leaves serum on the surface. HoMEso uses a stamping method — needles enter vertically and deliver serum directly through the hollow tip as you treat. That means the PDRN, Exosomes and B12 actually get into the skin, not just onto it. The difference in results is significant.
Yes. The HoMEso serum is 100% fragrance-free, formulated for sensitive skin, and made in Italy to EU safety standards. Each needle head is individually sterile-packed and single-use. We recommend a patch test on the inner wrist before your first full facial treatment.
The immediate glow and tightening effect lasts 3–5 days per treatment. The deeper collagen-building effect — driven by PDRN — continues to work after each session and compounds over the course of treatment. Results from a full 3-month course can last several months.
We ship to 70+ countries. Orders are dispatched within 24 hours (Monday–Friday). Standard delivery within Europe takes 3–5 business days. All orders are tracked — you'll receive a tracking link by email as soon as your order ships.
Avoid using over active breakouts, open skin or inflamed areas. HoMEso can be used on the rest of the face while avoiding those spots. Many customers with post-acne scarring report visible improvement with regular use. If you have severe or cystic acne, consult your dermatologist first.
Visibly reduce wrinkles and dark spots —
without injectables. At home.
Join 50,000+ customers who've experienced the difference PDRN & Exosomes make. 1-Month Kit from €89.90 · 3-Month Kit from €179.90. 30-day money-back guarantee.
1-Month from €89.90 · 3-Month from €179.90
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